Original Article
Zika Virus Viewed Through the Resonant Recognition Model. Unraveling New Avenues for Understanding and Managing a Serious Threat
Author(s):
José Luis Hernández Cáceres* and Graham Wright
Introduction: Zika Virus (ZIKV) infection is a major public health concern, affecting almost each country in the western hemisphere. A more than 20-fold increase in microcephaly risks is associated to ZIKV infection in pregnancy. A new vaccine is not expected before 2019, and alternative prophylactic and therapeutic approaches are encouraged. We expect that the Resonant Recognition Model, developed by Irena Cosic, might lay on the basis for an alternative approach to handle ZIKV.
Objective: We tried to identify the resonant frequencies associated to the ZIKV polyprotein and their use for an automatic taxonomy of different ZIKV strains. We put to test the hypothesis of interaction between ZIKV envelope protein and the AXL receptor, one of the plausible mechanisms proposed for ZIKVassociated microcephaly.
Results: Four r.. Read More»
DOI: 10.24105/ejbi.2018.14.1.5